"Cannabinoids"

Our product, (Cannabis Science) broadly described, is medical cannabis - a term which encompasses a wide variety of products, ranging from plants grown by patients for their own use to pharmaceutical products developed from one or more of the cannabinoid compounds found in the whole cannabis plant.
Cannabinoids are a group of terpenophenolic compounds present in Cannabis (Cannabis sativa L). Currently, 538 natural compounds were identified from this plant. 43 of these 108 are identified as cannabinoids, which are C21 compounds uniquely present in Cannabis sativa L. There are ten main types of cannabinoids and fourteen different cannabinoid subtypes. Tetrahydrocannabinol (THC) is the principal psychoactive ingredient in cannabis, but it also has other effects. Cannabidiol (CBD) and cannabinol (CBN) are the other two most prevalent natural cannabinoids and have received the most study. All three are listed as ingredients in Sativex®, the only multi-cannabinoid medicine currently approved for marketing (only in Canada.)
Cannabinoids were first discovered in the 1940s, when CBD and CBN were identified. THC was not identified until 1964, but by that time cannabis had been removed from the pharmacopeiae of most countries, making further research on the plant difficult
There are three general types of cannabinoids:
1Phytocannabinoids occur uniquely in the cannabis plant.
2Endogenous cannabinoids are produced in the bodies of humans and other animals.
3Synthetic cannabinoids are similar compounds produced in a laboratory. Forms of synthetic THC are available by prescription in a number of countries, including the US. In the US, synthetic THC is marketed as Marinol®. 

Phytocannabinoids, also called natural cannabinoids, herbal cannabinoids, and classical cannabinoids, are only known to occur naturally in significant quantity in the cannabis plant. They are concentrated in a viscous resin that is produced in glandular structures known as trichomes, and are most prevalent in the flowers of the female plants.

Cannabinoid receptors in the human body were not discovered until 1990. CB1 receptors are found primarily in the brain, specifically in the basal ganglia and in the limbic system, including the hippocampus. They are also found in the cerebellum and in both male and female reproductive systems.
CB1 receptors appear to be responsible for the euphoric and anti-convulsive effects of cannabis.
Cannabinoid pharmaceuticals, unlike many other pharmaceutical compounds, do not represent a risk factor for respiratory or cardiovascular failure. Cannabis has been called one of the safest drugs known by Federal Judge Young in 1977. In fact, there is no known lethal dose of cannabis. It has an estimated therapeutic index of 40,000 to one as compared to aspirin with a therapeutic index of 15.
CB2 receptors are found almost exclusively in the immune system, with the greatest density in the spleen. CB2 receptors appear to be responsible for the anti-inflammatory and possibly other therapeutic effects of cannabis.

The endocannabinoid system refers to a group of neuromodulators and receptors involved in a variety of physiological processes including appetite, pain sensation, mood, and memory. The system is named for endocannabinoids, the endogenous lipids that bind cannabinoid receptors (the same receptors that mediate the psychoactive effects of cannabis).

Science increasingly recognizes the role that endo-cannabinoids play in almost every major life function in the human body. Cannabinoids act as a bio regulatory mechanism for most life processes, which explains why medical cannabis has been recommended as a treatment for many diseases and ailments in anecdotal reports and scientific literature. Some of these ailments include: Pain, arthritic conditions, migraine headaches, anxiety, epileptic seizures, insomnia, loss of appetite, GERD (chronic heartburn), nausea, glaucoma, AIDS wasting syndrome, depression, bipolar disorder (particularly depression-manic-normal), multiple sclerosis, menstrual cramps, Parkinson's, trigeminal neuralgia (tic douloureux), high blood pressure, irritable bowel syndrome, and bladder incontinence.

Cannabis has been used medicinally for thousands of years in China, India and the Middle East. Of course, most traditional medicines were plant-based, but until recently no one knew how or why they worked. Modern science now routinely verifies the efficacy of this "folk medicine" tradition and the door is opening to a more systematic and effective use of cannabinoid therapies.

While cannabis was widely used in the West during the 19th century, the technology was lacking to detect and understand its active ingredients, to standardize dosages of those ingredients, and to effectively deliver those ingredients, owing largely to cannabis's non-water-solubility. Consequently, it became less widely used in the early 20th century and was eventually renamed "marijuana" and banned as part of a politically-driven prohibition craze. It was gradually removed from the pharmacopeiae of most advanced countries; research was discouraged, and when beneficial results were discovered, the studies were sometimes suppressed.
For example, when Senator Edward Kennedy (D-MA) was recently diagnosed with a form of brain cancer, malignant glioma, the media largely ignored reports from the medical cannabis community of studies showing that cannabinoids can kill glioma cancer cells.

Nearly a decade ago, the National Organization for the Reform of Marijuana Laws' weekly news release for December 31, 1998 reported that "Cell studies performed by researchers at Madrid's Universidad Complutense demonstrate that THC, one of the active compounds in marijuana, can induce cell death in certain brain tumor cells without affecting the surrounding healthy cells."
http://www.cannabisscience.com/products.html 

"HEMP PAPER"

The "DECLARATION" was written on "HEMP" Paper!

At the present rate of deforestation in the United States, it won't be long before we never see a tree, period. At the rate we are going, the United States will be stripped completely bare of all its forests in 50 years.
If the hemp pulp paper process of 1916 were in use today, it could replace 40-70% of all pulp paper form trees, including corrugated boxes, computer printout paper and paper bags. Imagine the effect this conversion to hemp paper alone would have on near-extinct species and all forms of wild life, on old-growth forests that are fast disappearing, on the quality of our water, soil, and air, as well as on our planet's sensitive ecosystem!

Farming only 6% of continental US acreage with biomass crops would provide all of America's gas and oil energy needs, ending dependence upon fossil fuels. Hemp is the only biomass source available that is capable of making the US energy-independent. Ultimately, the world has no other rational environmental choice but to give up fossil fuels.

Ever wonder why tree paper is so cheap? It's because we are subsidizing the true costs of production by borrowing from our own future and that of our children: imagine a world without trees and you'll realize the full impact, significance, and costs of cheap paper from trees. Hemp, unlike trees, grows to maturity in 6-8 months. There is no need to cut down 100 year old trees to make paper! Not only can hemp provide us with top-quality archival paper that's beautiful & strong and leaves a light footprint on this fragile planet of ours, it can also single-handedly put a stop to Greenhouse Effect, soil erosion, dependence on fertilizers and toxic chemicals, blue baby syndrome, pollution of the air, water, and soil, and so much more!

"Cancer"

"CANNABIS SCIENCE"

Research & Development


Description
Cancer (medical term: malignant neoplasm) is a class of diseases in which a group of cells display uncontrolled growth (division beyond the normal limits), invasion (intrusion on and destruction of adjacent tissues), and sometimes metastasis (spread to other locations in the body via lymph or blood). These three malignant properties of cancers differentiate them from benign tumors, which are self-limited, and do not invade or metastasize. Most cancers form a tumor but some, like leukemia, do not. The branch of medicine concerned with the study, diagnosis, treatment, and prevention of cancer is oncology.
Cancer affects people at all ages with the risk for most types increasing with age. Cancer caused about 13% of all human deaths in 2007 (7.6 million).
Cancers are caused by abnormalities in the genetic material of the transformed cells. These abnormalities may be due to the effects of carcinogens, such as tobacco smoke, radiation, chemicals, or infectious agents. Other cancer-promoting genetic abnormalities may randomly occur through errors in DNA replication, or are inherited, and thus present in all cells from birth. The heritability of cancers is usually affected by complex interactions between carcinogens and the host's genome.

Genetic abnormalities found in cancer typically affect two general classes of genes. Cancer-promoting oncogenes are typically activated in cancer cells, giving those cells new properties, such as hyperactive growth and division, protection against programmed cell death, loss of respect for normal tissue boundaries, and the ability to become established in diverse tissue environments. Tumor suppressor genes are then inactivated in cancer cells, resulting in the loss of normal functions in those cells, such as accurate DNA replication, control over the cell cycle, orientation and adhesion within tissues, and interaction with protective cells of the immune system.

Definitive diagnosis requires the histologic examination of a biopsy specimen, although the initial indication of malignancy can be symptomatic or radiographic imaging abnormalities. Most cancers can be treated and some cured, depending on the specific type, location, and stage. Once diagnosed, cancer is usually treated with a combination of surgery, chemotherapy and radiotherapy. As research develops, treatments are becoming more specific for different varieties of cancer. There has been significant progress in the development of targeted therapy drugs that act specifically on detectable molecular abnormalities in certain tumors, and which minimize damage to normal cells. The prognosis of cancer patients is most influenced by the type of cancer, as well as the stage, or extent of the disease. In addition, histologic grading and the presence of specific molecular markers can also be useful in establishing prognosis, as well as in determining individual treatments.
http://cannabisscience.com/research-a-development/cancer.html 

Brain Trauma"

Cannabis Science"

Research & Development

Description
Traumatic brain injury (TBI, also called intracranial injury) occurs when an outside force traumatically injures the brain. TBI can be classified based on severity, mechanism (closed or penetrating head injury), or other features (e.g. occurring in a specific location or over a widespread area). Head injury usually refers to TBI, but is a broader category because it can involve damage to structures other than the brain, such as the scalp and skull.
TBI is a major cause of death and disability worldwide, especially in children and young adults. Causes include falls, vehicle accidents, and violence. Prevention measures include use of technology to protect those who are in accidents, such as seat belts and sports or motorcycle helmets, as well as efforts to reduce the number of accidents, such as safety education programs and enforcement of traffic laws.
Brain trauma can be caused by a direct impact or by acceleration alone. In addition to the damage caused at the moment of injury, brain trauma causes secondary injury, a variety of events that take place in the minutes and days following the injury. These processes, which include alterations in cerebral blood flow and the pressure within the skull, contribute substantially to the damage from the initial injury.
TBI can cause a host of physical, cognitive, emotional, and behavioral effects, and outcome can range from complete recovery to permanent disability or death. The 20th century has seen critical developments in diagnosis and treatment which have decreased death rates and improved outcome. These include imaging techniques such as computed tomography and magnetic resonance imaging. Depending on the injury, treatment required may be minimal or may include interventions such as medications and emergency surgery. Physical therapy, speech therapy, and occupational therapy may be employed for rehabilitation.
 http://cannabisscience.com/research-a-development/brain-trauma.html

"Cannabis Science"

Research & Development

Description
Hypertension is a chronic medical condition in which the blood pressure is elevated. It is also referred to as high blood pressure or shortened to HT, HTN or HPN. The word "hypertension", by itself, normally refers to systemic, arterial hypertension.
Hypertension can be classified as either essential (primary) or secondary. Essential or primary hypertension means that no medical cause can be found to explain the raised blood pressure. It is common. About 90-95% of hypertension is essential hypertension. Secondary hypertension indicates that the high blood pressure is a result of (i.e., secondary to) another condition, such as kidney disease or tumours (adrenal adenoma or pheochromocytoma).
Persistent hypertension is one of the risk factors for strokes, heart attacks, heart failure and arterial aneurysm, and is a leading cause of chronic renal failure. Even moderate elevation of arterial blood pressure leads to shortened life expectancy. At severely high pressures, defined as mean arterial pressures 50% or more above average, a person can expect to live no more than a few years unless appropriately treated. Beginning at a systolic pressure (which is peak pressure in the arteries, which occurs near the end of the cardiac cycle when the ventricles are contracting) of 115 mmHg and diastolic pressure (which is minimum pressure in the arteries, which occurs near the beginning of the cardiac cycle when the ventricles are filled with blood) of 75 mmHg (commonly written as 115/75 mmHg), cardiovascular disease (CVD) risk doubles for each increment of 20/10 mmHg.

http://cannabisscience.com/research-a-development/high-blood-pressure.html

Research & Development Overview

 Research & Development
Endocannabinoids are marijuana-like compounds that are produced by most animals, including all vertebrates. Quite surprisingly, the endocannabinoids system has an all-pervasive role in maintaining homeostasis (biochemical balance). All living creatures suffer from a common biochemical imbalance, we are all aging. Today, in developed countries, most people suffer and die from age-related illnesses including cardiovascular diseases, autoimmune diseases, neurological disorders, and cancers. Modern science from an abundance of peer-reviewed publications indicates that stimulating the endocannabinoid system benefits all of these conditions.
We understand what patients need and want. As a result, the Company offers the savvy investor a novel opportunity to participate in producing groundbreaking products that will impact some of the most important medical concerns of our times. In addition to targeting the billion dollars a year pain management industry, the Company is uniquely positioned to develop products for high blood pressure, cancer, HIV, and the bird flu.
Cannabis Science™ is in a unique position to pursue the development of blood pressure and cancer medications. The endocannabinoid system normally regulates blood pressure through its capacity to dilate blood vessels and reduce adrenergic stimuli. Additionally, there is a developing body of evidence that shows both the tumor killing properties of endo- and phyto- cannabinoids, and their ability to inhibit metastasis in a variety of cancers.
Cannabis Science™ works with world authorities on phytocannabinoid science developing cannabis-based therapeutics that will holistically promote health by restoring biochemical balance. By adhering to underlying scientific principles, the Company will manipulate all-pervasive phytocannabinoid processes to target a variety of disparate illnesses.
An emergent global threat is that the bird flu, a strain (H5N1) of influenza A, will evolve to infect human beings. The typical yearly variation in flu strains has been an ongoing challenge and concern to researchers developing preventative and therapeutic products. The high degree of variability found in the influenza A virus is an intrinsic property of the virus's chromosomal structure and how it replicates. Overcoming the difficulties encountered in this field take on even greater importance with the threat of the bird flu jumping species bird into the human population.
The bird flu differs from other strains by its enhanced capacity to kill infected individuals. The common cause of death with this strain is that patients developed adult respiratory distress syndrome (ARDS). ARDS is in excess inflammatory response that leads to apoptosis and organ failure. The Company's approach will mimic how the human body uses endocannabinoids to regulate immune activity and cell survival.
The magnitude of the bird flu threat is so great that positive results from this arm of our research would greatly facilitate the acceptance of our cannabis-based pharmaceuticals. There should be highly profitable additional applications that result.
More recently, revolutionary scientific breakthroughs in understanding the HIV infective and developmental processes have been discovered that will lead to entirely new therapeutic approaches.
Cannabis Science™ is uniquely positioned to explore insights that indicate an intrinsic link between novel cancer and HIV technologies and the cannabinoid system. Published experiments by a leading AIDS researcher, Dr. Donald Abrams, suggest that counter to conventional wisdom, smoked marijuana does not result in an increased HIV viral load. In fact, there were suggestions of a reduced viral load. We expect to show that our pharmaceuticals will enhance biochemical markers that are indicative of a successful HIV therapy based on recent paradigm breaking discoveries.
Overall, our product development will follow two parallel paths. We will create pharmaceuticals with and without psychoactive properties. Both of these lines will have numerous health benefits for treating illnesses and for general health maintenance. Both psycho and non-psychoactive products with demonstrated therapeutic efficacy for these globally important illnesses will facilitate entry first into the Canadian marketplace. Proven efficacy in the Canadian market should then open the US and global markets.

Traders Nation Interview with CBIS President

Cannabis Science a License to Make Jimi Hendrix .....

Cannabis Science Signs Andrew Pitsicalis as International Brand and Licensing Director, Rockin Artwork Grants Cannabis Science a License to Make Jimi Hendrix Image and Likeness Related Products for Advertising, Manufacturing, Sales and Marketing April 20, 2012 COLORADO SPRINGS, Colo.--(BUSINESS WIRE)--Cannabis Science, Inc. (OTCBB: CBIS.OB - News) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is thrilled to welcome Andrew Pitsicalis as International Brand and Licensing Director. Mr. Pitsicalis has been CEO of Rockin Artwork since 2010. Rockin Artwork is an intellectual property company, which manages or owns images and art by artists for Licensing and Fine Art. Their works include those by Mike and Dasha Biggs, David Garibaldi, Justin Farano, Dan Kennedy and more. Leon Hendrix, Jimi Hendrix's brother, is an owner and the spiritual guide of the company and their collection includes Jimi Hendrix images and art for merchandise and licensing. Rockin Artwork has granted Cannabis Science a co-branding license to allow Cannabis Science to advertise, manufacture, and brand Jimi Hendrix images and likenesses and to make Jimi Hendrix image and likeness related products and the marketing thereof. Leon Hendrix is pleased to endorse Cannabis Sciences’ role in creating great products his brother Jimi Hendrix would be proud of. When asked his thoughts were joining Cannabis Science Inc., Mr. Pitsicalis said, ”I look forward to creating great quality products. Having experience licensing properties that span a fan base of 2 billion people worldwide, I have licensed products in mass market retail stores around the globe. You can find Pitsicalis’ companies, licensed products in places like, Walmart, Target, Kohls, JC Penny, Urban Outfitters, Old Navy and other mass retail chains." Mr. Pitsicalis’s role at Cannabis Science is to help build the brands of Cannabis Science. This will include consulting and brand management of Cannabis Science product lines, manufacture and develop the licensing platform for Cannabis Science, Patents and Trademarks. Mr. Pitsicalis will facilitate the advertising and licensing of products and branding of Cannabis Science. Pitsicalis will be selecting advertising campaigns for brand and product recognition. There are plans in the future to eventually license our biotechnology to pharmaceutical companies and other hemp related manufacturing licenses. Andrew has extensive connections to doctors, intellectual property, and venues for future medical cannabis conferences, all of which are invaluable to Cannabis Science. Mr. Pitsicalis, legal victories in Federal Court for Jimi Hendrix Intellectual property rights will give Cannabis Science a seasoned component to licensing and branding. Andrew will be seated on the Policy Advisory Board for the company and we are pleased to have his input from his legal and licensing knowledge. Cannabis Science is excited to welcome another talented and professional individual into the fold and looks forward to the endless promotion opportunities available through Andrew Pitsicalis. About Cannabis Science, Inc. Cannabis Science, Inc. is at the forefront of pharmaceutical grade medical marijuana research and development. The second formulations will address the needs of patients choosing to use concentrated cannabis extracts to treat their ailments. Eventually, all Americans will have access to a safe and effective FDA approved medicine regardless of which state they live in. To maintain that marijuana is a dangerous, addictive drug with no medical value is scientifically absurd. Cannabis medicines, with no effective lethal dose, are far safer than aspirin, acetaminophen, and most other OTC drugs that kill thousands of Americans every year. The Company works with world authorities on phytocannabinoid science targeting critical illnesses, and adheres to scientific methodologies to develop, produce and commercialize phytocannabinoid-based pharmaceutical products. In sum, we are dedicated to the creation of cannabis-based medicines, both with and without psychoactive properties, to treat disease and the symptoms of disease, as well as for general health maintenance. Forward Looking Statements This Press Release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Act of 1934. A statement containing works such as "anticipate," "seek," intend," "believe," "plan," "estimate," "expect," "project," "plan," or similar phrases may be deemed "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Some or all of the events or results anticipated by these forward-looking statements may not occur. Factors that could cause or contribute to such differences include the future U.S. and global economies, the impact of competition, and the Company's reliance on existing regulations regarding the use and development of cannabis-based drugs. Cannabis Science, Inc. does not undertake any duty nor does it intend to update the results of these forward-looking statements. Contact: Cannabis Science Inc. Dr. Robert J. Melamede President & CEO 1-888-889-0888 info@cannabisscience.com or Robert Kane Investor Relations Management 1-561-234-6929 rkane@cannabisscience.com

BREAKING NEWS!!!!!!

April 4, 2012 COLORADO SPRINGS, Colo.--(BUSINESS WIRE)-- Cannabis Science, Inc. (OTCBB: CBIS.OB - News) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products is happy to report that patient #2, who had a Squamous cell carcinoma on her arm, has received her biopsy report. It confirms what was visually apparent from the photo-documentation on our website. Her biopsy was free of cancer cells and she will not need any surgical procedure. Nevertheless, the patient will continue with her self-administered topical application of extracts for a while longer to minimize any chance of any surviving cancer cells in areas beyond what was biopsied. Cannabis Science Inc., President & CEO, Dr. Robert Melamede Ph.D., stated, “Squamous cell carcinomas have a much greater invasive potential than is typical of basal cell carcinomas. Photo-documentation of topical cannabis extract treatments of patient #2 and patient #3 dramatically demonstrate how the treatment appear to extrude the subcutaneous tumor to the surface as the killing and subsequent healing proceeds. Patient #3 reports continued progress as his tumors appear to shrink and the pain levels continue to improve. The patient's wife commented that about 75% of the large tumor mass is gone. We will continue with ‘live updates’ as new pictures and physician reports are made available to us.” You can view the patient’s photographs during the treatment process, as well as the full biopsy report from the physician, on the Cannabis Science website www.cannabisscience.com. Click the button “View Images of 2nd Self-Medicated Patient & The Apparent Success” to view the full biopsy report, photos and additional information. About Cannabis Science, Inc. Cannabis Science, Inc. is at the forefront of pharmaceutical grade medical marijuana research and development. The second formulations will address the needs of patients choosing to use concentrated cannabis extracts to treat their ailments. Eventually, all Americans will have access to a safe and effective FDA approved medicine regardless of which state they live in. To maintain that marijuana is a dangerous, addictive drug with no medical value is scientifically absurd. Cannabis medicines, with no effective lethal dose, are far safer than aspirin, acetaminophen, and most other OTC drugs that kill thousands of Americans every year. The Company works with world authorities on phytocannabinoid science targeting critical illnesses, and adheres to scientific methodologies to develop, produce and commercialize phytocannabinoid-based pharmaceutical products. In sum, we are dedicated to the creation of cannabis-based medicines, both with and without psychoactive properties, to treat disease and the symptoms of disease, as well as for general health maintenance. Forward Looking Statements This Press Release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Act of 1934. A statement containing works such as "anticipate," "seek," intend," "believe," "plan," "estimate," "expect," "project," "plan," or similar phrases may be deemed "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Some or all of the events or results anticipated by these forward-looking statements may not occur. Factors that could cause or contribute to such differences include the future U.S. and global economies, the impact of competition, and the Company's reliance on existing regulations regarding the use and development of cannabis-based drugs. Cannabis Science, Inc. does not undertake any duty nor does it intend to update the results of these forward-looking statements. Contact: Cannabis Science Inc. Dr. Robert J. Melamede, 1-888-889-0888 President & CEO info@cannabisscience.com www.cannabisscience.com or Robert Kane, 1-561-234-6929 VP Investor Relations rkane@cannabisscience.com info@cannabisscience.com www.cannabisscience.com

Got Cancer?

GOT CANCER?-Cannabis Science (C. S.) Negotiates Commercialization Deal to Bring C. S. Brand Formulations Immediately into CALIFORNIA Market
http://bit.ly/tiKnS5
-We've (C. S.) a variety of Cannabis-based formulations from CANCER to pain management http://bit.ly/vKoUPv
-2nd Self Medicated Medical Cannabis Cancer Patient Reports C. S. Brand Extracts KILLING Cancer Cells http://bit.ly/uu3z7c
-C. S. Publishes OVER 800 Peer-Reviewed Cannabis and Cancer References From Scientists http://bit.ly/vhW6kY

Cannabis Cancer response on 2009 04 22 at 09 12

Cancer Cure - Cannabis & Cannabinoids,by Robert Melamede,PhD

*** Cannabinoids and tumor inhibition in the news again this week!:

http://www.mapinc.org/drugnews/v08/n076/a02.html
On this video filmed in 2006, Dr. Robert Melamede, Professor of Biology at the University of Colorado, explains how the body's Endo-Cannabinoid system (and plant based Cannabinoids as suppliment) kills cancer cells and inhibits tumor growth.
Refering to 1974 U.S.government-sponsored study when THC was found to slow growth of cancer cells
http://projectcensored.org/publications/2001/22.html
and to recent research in Spain finding that THC stopped brain tumors in rats and protected surrounding nerve tissue, demonstrating neuroprotectant aspect of Cannabinoids.
PDF of Dr. Guzman's research:
http://americanmarijuana.org/Guzman-Cancer.pdf
Refering to "Homeostatic Regulation" of several body systems by Cannabinoids, Dr. Melamede concludes that Cannabis is indeed a "Miracle Drug", also recommending hemp oil as excellent source of EFAs the body needs to fight disease.
View Dr. Robert Melamede at 2004 Cannabis Therapeutics Conference:
"Holistic Biochemistry of Cannabinoids"
http://video.google.com/videoplay?docid=4179107660421413341
Dr. Guzman will be at the 2008 Cannabis Therapeutics Conference this April. More info:
http://www.medicalcannabis.com

Comment on Rick Simpson's Work

• Dr.Melamede

Dr.Melamede (Cannabis Science)

Dr. Robert Melamede CEO of Cannabis Science, Inc. talks to StockGoodies Radio about the medical and physiological benefits of medicinal marijuana.

         

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The EssiacHempLaetrile CANCER / BIG PHARMA song!

"Whose Oil And Who Can You Trust?

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"Basil Cell Carcinoma"

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Science Support's Rick Simpson's Work""

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Who is NOT willing to interview Rick Simpson?

National Film Board of Canada The National Film Board (NFB) is Canada's public film producer and distributor.

Dr. Oz

Health Canada Health Canada (Government of Canada)

National Cancer Institute US The United States Government's cancer information authority.

Canadian Cancer Society

AmerCancerSociety

Cancer Research UK Cancer Research UK is the world's leading independent charity dedicated to cancer research.

United Nations The United Nations Channel

MD Anderson Cancer Center The University of Texas MD Anderson Cancer Center

Memorial Sloan-Kettering The Memorial Sloan-Kettering Cancer Center (MSKCC) Channel

The Oprah Winfrey Network

The Onion The Onion News Network is an arm of The Onion, America's FInest News Source.

Associated Press The Associated Press is the essential global news network. Founded in 1846, AP today is...

Deepak Chopra Global-Official

JREF

Alex's Jones  Official Channel

KILL CANCER

Rick Simpson … “Hemp Oil Cures Cancer”Dr. Melamede … “Cannabinoids kill Cancer Cells”Dr. Di Marzo … “THC exhibits anti –tumor effects on various Cancer Cell types”SETH Group “Herbal (THC) compound kills brain Cancer Cells –but not normal brain cells.”Dr. Guzman … “THC can promote the autophagic death of human and mouse Cancer Cells”Dr. Mechoulam … “we gave THC oil drops 400 times to children 1 -13 years old with Cancer & prevented vomiting & nausea 100%

Cancer Cure=HEMP OIL

CANCER CURE = HEMP OIL Since 1964 –present The National Institutes of Health (NIH) in United States has been the MAJOR financial supporter to Dr. Raphael Mechoulam in Israel for his research into CANNABIS.SOURCE: Endocannabinoid System Network (ECSN)

Rick Simpson

Rick Simpson's Official website http://www.phoenixtears.ca/

"After a serious head injury in 1997, Rick Simpson sought relief from his medical condition through the use of medicinal Hemp Oil. When Rick discovered that the Hemp Oil (with its high concentration of T.H.C.) cured Cancers and other illnesses, he tried to share it with as many people as he could free of charge - curing and controlling literally hundreds of people's illnesses... but when the story went public, the long arm of the law snatched the medicine - leaving potentially thousands of people without their Cancer treatments - and leaving Rick with unconsitutional charges of possessing and trafficking marijuana!" -Christian Laurette, Producer & Director of "RUN FROM THE CURE - The Rick Simpson Story"

"Cannabinoid

EssiacHempLaetrile says: July 13, 2011

The Medical Establishment named them specifically “Cannabinoid Receptors” for a reason: CB1 & CB2 are in our bones, brain, C cells, central nervous system, colon, dendritic cells, heart, immune system, intestines, kidney, liver, macrophages, pancreas, retina, ribs, skin, spleen, testis, uterus, vascular system, white blood cells & bone marrow (stem cells) etc. Without the 600+ Million year old Endocannabinoid System*, Stem Cells would act like a car without a driver. *Dr. Guy, GW Pharmaceuticals

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EssiacHempLaetrile Says :

July 13, 2011

3:25 FIRST oral therapy available for Canada “On April 19, 2005 Health Canada approved Sativex, a Cannabis-based drug for the treatment of Multiple Sclerosis-related pain. The drug consists of various extracts from the Cannabis plant. It is administered via a spray into the mouth. The Multiple Sclerosis Society of Canada welcomes the approval of Sativex, which will provide people with MS and their physicians another choice in treating pain, which is a common symptom of the disease.”

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"parent's worst nightmare"

To call what the Hyde family has been through a "parent's worst nightmare" sounds like a horrible cliche. But, it's hard to imagine what else you could call it. Their two-year old son Cash was diagnosed last year with a stage 4 brain tumor; he nearly died more times than they can count. He was miserable from the chemotherapy coursing through his body. Until his dad made a controversial decision to give cannabis to his young son. KXLY 4's Melissa Luck reports.

"Cure The World" (Part One)

Contacted By GW Pharmaceuticals

EssiacHempLaetrile "Around Sept. 2010, we were contacted by GW Pharmaceuticals (works with world's leading Cannabinoid scientists in 7 Universities: Aberdeen, Hebrew, Buckingham, Reading, Complutense, Naples Frederico II & Insubria and The Institute of Biomolecular of the National Research Council, Italy) asked if I'd collaborate with them. But there's NO way in the world that I'd collaborate with a Pharmaceutical company involved with this substance, it belongs to the people!"

RICK SIMPSON http://bit.ly/sWmelZ

Rick Simpson's Oil

January 31, 2012 04:20 PM Cannabis Therapeutics ☏ (719) 633-7124 907 E Fillmore St. Colorado Springs, Colorado 80907 US FOR SALE: Only Colorado Residents, Rick Simpson's Cancer Cure ALL Hemp Oil

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Appendix Isn't Useless at All!

By Duke Medicine News and Communications

DURHAM, NC -- Long denigrated as vestigial or useless, the appendix now appears to have a reason to be -- as a "safe house" for the beneficial bacteria living in the human gut.

Drawing upon a series of observations and experiments, Duke University Medical Center investigators postulate that the beneficial bacteria in the appendix that aid digestion can ride out a bout of diarrhea that completely evacuates the intestines and emerge afterward to repopulate the gut. Their theory appears online in the Journal of Theoretical Biology.

"While there is no smoking gun, the abundance of circumstantial evidence makes a strong case for the role of the appendix as a place where the good bacteria can live safe and undisturbed until they are needed," said William Parker, PhD, assistant professor of experimental surgery, who conducted the analysis in collaboration with R. Randal Bollinger, MD, PhD, Duke professor emeritus in general surgery.

The appendix is a slender two- to four-inch pouch located near the juncture of the large and small intestines. While its exact function in humans has been debated by physicians, it is known that there is immune system tissue in the appendix.


Continue To Full Article-http://www.dukehealth.org/health_library/news/10151

Antineoplastic activity of cannabinoids

A.E. Munson, L.S. Harris, M.A. Friedman, W.L. Dewey, and R.A. Carchman

Journal of the National Cancer Institute, Vol. 55, No. 3, September 1975

Supported by Public Health Service grant DA00490 from the National Institute on Drug Abuse, Health Services & Mental Health Administration; by a grant from the Alexander and Margaret Stewart Trust Fund; and by an institutional grant from the American Cancer Society.

Department of Pharmacology and the MCV/VCU Cancer Center, Medical College of Virginia, Virginia Commonwealth University. Richmond, Va. 23298

Abstract

Lewis lung adenocarcinoma growth was retarded by the oral administration of delta-9-tetrahydrocannabinol, delta-8-tetrahydrocannabinol, and cannabinol (CBN), but not cannabidiol (CBD). Animals treated for 10 consecutive days with delta-9-THC, beginning the day after tumor implantation, demonstrated a dose-dependent action of retarded tumor growth. Mice treated for 20 consecutive days with delta-8-THC and CBN had reduced primary tumor size. CBD showed no inhibitory effect on tumor growth at 14, 21, or 28 days. Delta-9-THC, delta-8-THC, and CBN increased the mean survival time (36% at 100 mg/kg, 25% at 200 mg/kg, and 27% at 50 mg/kg;, respectively), whereas CBD did not. Delta-9-THC administered orally daily until death in doses of 50, 100, or 200 mg/kg did not increase the life-spans of (C57BL/6 X DBA/2) F (BDF) mice hosting the L1210 murine leukemia. However, delta-9-THC administered daily for 10 days significantly inhibited Friend leukemia virus-induced splenomegaly by 71% at 200 mg/kg as compared to 90.2% for actinomycin D. Experiments with bone marrow and isolated Lewis lung cells incubated in vitro with delta-8-THC and delta-9-THC showed a dose-dependent (10 -4 10 -7) inhibition (80-20%, respectively) of tritiated thymidine and 14C -uridine uptake into these cells. CBD was active only in high concentrations (10 -4)

Introduction

Investigations into the physiologic processes affected by the psychoactive constitutuents of marihuana [delta-9-tetrahydrocannabinol (delta-9-THC) and delta-8-tetrahydrocannabinol (delta-8-THC)] purified from Cannabis sativa are extensive (1). However, only recently have attempts been made to elucidate the biochemical basis for their cytotoxic or cytostatic activity. Leuchtenberger et al. (2) demonstrated that human lung cultures exposed to marihuana smoke showed alterations in DNA synthesis, with the appearance of anaphase bridges. Zimmerman and McClean (3), studying macromolecular synthesis in Tetrahymena, indicated that very low concentrations of delta-9-THC inhibited RNA, DNA, and protein synthesis and produced cytolysis. Stenchever et al. (4) showed an increase in the number of damaged or broken chromosomes in chronic users of marihuana. Delta-9-THC administered iv inhibited bone marrow leukopoieses (5), and Kolodny et al. (6) reported that marihuana; may impair testosterone secretion and spermatogenesis.

Furthermore, Nahas et al. (7) showed that in chronic marihuana users there is a decreased lymphocyte reactivity to mitogens as measured by thymidine uptake. These and other (8) observations suggest that marihuana (delta-9-THC) interferes with vital cell biochemical processes, though no definite mechanism has yet been established. A preliminary report from this laboratory (9) indicated that the ability of delta-9-THC to interfere with normal cell functions might prove efficacious against neoplasms. This report represents an effort to test various cannabinoids in several in vivo and in vitro tumor systems to determine the kinds of tumors that are sensitive to these compounds and reveal their possible biochemical sites of action(s).

Continue To Full Article Source-http://www.ukcia.org/research/AntineoplasticActivityOfCannabinoids/index.php

Pot Shrinks Tumors

Pot Shrinks Tumors; Government Knew in '74
In 1974 researchers learned that THC, the active chemical in marijuana, shrank or destroyed brain tumors in test mice. But the DEA quickly shut down the study and destroyed its results, which were never replicated -- until now.






February, 2000 when researchers in Madrid announced they had destroyed incurable brain tumors in rats by injecting them with THC, the active ingredient in cannabis.

The Madrid study marks only the second time that THC has been administered to tumor-bearing animals; the first was a Virginia investigation 26 years ago. In both studies, the THC shrank or destroyed tumors in a majority of the test subjects.

Most Americans don't know anything about the Madrid discovery. Virtually no major U.S. newspapers carried the story, which ran only once on the AP and UPI news wires, on Feb. 29, 2000.

The ominous part is that this isn't the first time scientists have discovered that THC shrinks tumors. In 1974 researchers at the Medical College of Virginia, who had been funded by the National Institute of Health to find evidence that marijuana damages the immune system, found instead that THC slowed the growth of three kinds of cancer in mice -- lung and breast cancer, and a virus-induced leukemia.

The DEA quickly shut down the Virginia study and all further cannabis/tumor research, according to Jack Herer, who reports on the events in his book, "The Emperor Wears No Clothes." In 1976 President Gerald Ford put an end to all public cannabis research and granted exclusive research rights to major pharmaceutical companies, who set out -- unsuccessfully -- to develop synthetic forms of THC that would deliver all the medical benefits without the "high."

Continue To Full Article-http://www.alternet.org/story/9257/?page=entire

Cannabis destroys cancer cells... reveals research at Barts and The London, Queen Mary's School of Medicine and Dentistry

Researchers investigating the role of cannabis in cancer therapy reveal it has the potential to destroy leukaemia cells, in a paper published in the March 2006 edition of Letters in Drug Design & Discovery. Led by Dr Wai Man Liu, at Barts and the London, Queen Mary’s School of Medicine and Dentistry, the team has followed up on their findings of 2005 which showed that the main active ingredient in cannabis, tetrahydrocannabinol, or THC, has the potential to be used effectively against some forms of cancer. Dr Liu has since moved to the Institute of Cancer in Sutton where he continues his work into investigating the potential therapeutic benefit of new anti-cancer agents.

It has previously been acknowledged that cannabis-based medicines have merit in the treatment of cancer patients as a painkiller; appetite stimulant and in reducing nausea, but recently evidence has been growing of its potential as an anti-tumour agent. The widely reported psychoactive side effects and consequent legal status of cannabis have, however, complicated its use in this capacity. Although THC and its related compounds have been shown to attack cancer cells by interfering with important growth-processing pathways, it has not hitherto been established exactly how this is achieved.  

http://www.qmul.ac.uk/qmul/news/newsrelease.php?news_id=175

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